Genetic Variation of Neurotropic and Non-neurotropic Murine Coronaviruses
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چکیده
منابع مشابه
Murine coronaviruses: isolation and characterization of two plaque morphology variants of the JHM neurotropic strain.
Two plaque-size variants of the neurotropic JHM strain of mouse hepatitis virus have been isolated from the virus stock after eight serial passages in suckling mouse brain. One variant, JHM-DL, produces large plaques, while the other, JHM-DS, produces small plaques in tissue culture. DS replicates more slowly, has a lower virus yield in vitro, and is less virulent for mice than DL. They also di...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1981
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-54-1-67